Patients tolerant of full IV dose (15 mg): 50 mg orally every 6 hours starting 15 minutes after the last IV dose and continued for 48 hours.Initial dose: 5 mg IV every 2 minutes as tolerated for 3 doses Usual Adult Dose for Myocardial Infarction Increase dose at weekly intervals until optimum clinical response has been obtained or pronounced slowing of heart rate occurs.Metoprolol succinate extended release tablets: 100 mg orally once a day.Metoprolol tartrate immediate release tablets: 50 mg orally twice a day.Doses above 400 mg per day have not been studied.Maintenance dose: 100 to 400 mg orally once a day Initial dose: 25 to 100 mg orally once a day METOPROLOL SUCCINATE EXTENDED RELEASE TABLETS:
Beta-1 selectivity diminishes as the dose is increased. Lower once-daily doses may not maintain full effect at the end of the 24-hour period larger or more frequent daily doses may be required.Doses above 450 mg per day have not been studied.May increase dose at weekly, or longer, intervals.Maintenance dose: 100 to 450 mg orally per day Initial dose: 100 mg orally per day in single or divided doses METOPROLOL TARTRATE IMMEDIATE RELEASE TABLETS: